Postorgasmic Illness Syndrome (POIS) in 45 Dutch Caucasian Males: Clinical Characteristics and Evidence for an Immunogenic Pathogenesis (Part 1)

The combination of allergic and systemic flu‐like reactions post‐ejaculation together with a positive skin‐prick test in the majority of males underscores the hypothesis of an “immunogenic” etiology of POIS, e.g., that POIS is caused by Type‐1 and Type‐IV allergy to the males' own semen, as soon it is triggered by ejaculation. Waldinger MD, Meinardi MMHM, Zwinderman AH, and Schweitzer DH. Postorgasmic illness syndrome (POIS) in 45 Dutch Caucasian males: Clinical characteristics and evidence for an immunogenic pathogenesis (Part 1).