Radiation‐Induced Erectile Dysfunction Using Prostate‐Confined Modern Radiotherapy in a Rat Model

We demonstrated time‐dependent ED following image‐guided stereotactic RT. Our results imply that reduction of neuronal NOS expression in cavernous nerve could trigger consecutive reduction of smooth muscle content as well as blood perfusion in CC that resulted in corporal veno‐occlusive dysfunction. Present study could be a cornerstone to future research that may bring comprehensive scientific understanding of radiation‐induced ED. Kimura M, Yan H, Rabbani Z, Satoh T, Baba S, Yin F‐F, Polascik TJ, Donatucci CF, Vujaskovic Z, and Koontz BF. Radiation‐induced erectile dysfunction using prostate‐confined modern radiotherapy in a rat model. J Sex Med 2011;8:2215-2226.