Post‐Translational Inactivation of Endothelial Nitric Oxide Synthase in the Transgenic Sickle Cell Mouse Penis

These findings provide a molecular basis for chronically reduced eNOS function in the penis by SCD, which involves decreased eNOS phosphorylation on Ser‐1177 and decreased eNOS‐HSP90 interaction. Musicki B, Champion HC, Hsu LL, Bivalacqua TJ, and Burnett AL. Post‐translational inactivation of endothelial nitric oxide synthase in the transgenic sickle cell mouse penis. J Sex Med 2011;8:419-426.