کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4271599 1610921 2011 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Exposure to Phosphodiesterase Type 5 Inhibitors Stimulates Aromatase Expression in Human Adipocytes in vitro
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی اورولوژی
پیش نمایش صفحه اول مقاله
Exposure to Phosphodiesterase Type 5 Inhibitors Stimulates Aromatase Expression in Human Adipocytes in vitro
چکیده انگلیسی
Our results demonstrate that PDE5 is expressed in human visceral adipocytes and that acute exposure to PDE5i selectively stimulates ARO expression, which is related to a specific PDE5 blockade. We speculate that modulation of ARO activity by PDE5i could be one of the mechanisms responsible, at least in part, for the beneficial effects of PDE5i on endothelial and metabolic functions. Aversa A, Caprio M, Antelmi A, Armani A, Brama M, Greco EA, Francomano D, Calanchini M, Spera G, Luigi LD, Rosano GMC, Lenzi A, Migliaccio S, and Fabbri A. Exposure to phosphodiesterase type‐5 inhibitors stimulates aromatase expression in human adipocytes in vitro. J Sex Med 2011;8:696-704.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Sexual Medicine - Volume 8, Issue 3, March 2011, Pages 696-704
نویسندگان
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