Exogenous Testosterone and Estrogen Affect Bladder Tissue Contractility and Histomorphology Differently in Rat Ovariectomy Model

Either estradiol or testosterone replacement alone or in combination prevents significant alterations in bladder tissue histology following ovariectomy whereas both affect the bladder tissue contractility. Thus, combination treatment appears to be the best method to restore both contractility and histomorphology of bladder tissue after ovariectomy. Tanidir Y, Ercan F, and Tarcan T. Exogenous testosterone and estrogen affect bladder tissue contractility and histomorphology differently in rat ovariectomy model.