The Relaxation Induced by Uroguanylin and the Expression of Natriuretic Peptide Receptors in Human Corpora Cavernosa

UGN relaxes HCC strips by a guanylate cyclase and Kca-channel-dependent mechanism. These findings obtained in HCC reveal that the natriuretic peptide receptors are potential targets for the development of new drugs for the treatment of erectile dysfunction. Sousa CM, Havt A, Santos CF, Arnaud-Batista FJ, Cunha KMA, Cerqueira JBG, Fonteles MC, and Nascimento NRF. The relaxation induced by uroguanylin and the expression of natriuretic peptide receptors in human corpora cavernosa.