ORIGINAL RESEARCH-BASIC SCIENCE: Initial Characterization of Hydrogen Sulfide Effects in Female Sexual Function

These pilot studies clearly indicate the smooth muscle relaxant effect of H2S in female genital tract, mediating through cyclic adenosine 3′:5′-monophosphate, nitric oxide-cyclic guanosine monophosphate and K+ATP channels. Taken together with biochemical and molecular evidences for endogenous formation, H2S pathway could be a contributing factor in female sexual responses. Srilatha B, Lingxu H, Adaikan GP, and Moore PK. Initial characterization of hydrogen sulfide effects in female sexual function. J Sex Med 2009;6:1875-1884.