Delay of Ejaculation Induced by SB-277011, a Selective Dopamine D3 Receptor Antagonist, in the Rat

As a whole, the present data demonstrate the specific and primary role of D3 receptors in the expulsion phase of ejaculation and provide preclinical evidence for the investigation of the therapeutic potential of D3 antagonism for treating premature ejaculation. Clément P, Pozzato C, Heidbreder C, Alexandre L, Giuliano F, and Melotto S. Delay of ejaculation induced by SB-277011, a selective dopamine D3 receptor antagonist, in the rat. J Sex Med **;**:**-**.