The Effects of Citalopram and Fluoxetine on Sexual Behavior in Healthy Men: Evidence of Delayed Ejaculation and Unaffected Sexual Desire. A Randomized, Placebo‐Controlled, Double‐Blind, Double‐Dummy, Parallel Group Study

The treatment with citalopram or with fluoxetine was confirmed to delay ejaculation, but was significant only for citalopram. Citalopram and fluoxetine did not affect sexual desire. Citalopram and fluoxetine did not directly affect penile erection as objectively assessed by RigiScan, although an impairment in the subjective assessment of erectile function was observed, but was significant only for citalopram, and it was thought to be a possible consequence of the delayed ejaculation perceived as a trouble. Madeo B, Bettica P, Milleri S, Balestrieri A, Granata ARM, Carani C, and Rochira V. The effects of citalopram and fluoxetine on sexual behavior in healthy men: Evidence of delayed ejaculation and unaffected sexual desire. A randomized, placebo‐controlled, double‐blind, double‐dummy, parallel group study. J Sex Med 2008;5:2431-2441.