REVIEWS: Pathways of Sexual Desire

Drugs that stimulate the activation of hypothalamic dopamine or that blunt endocannabinoid or serotonin release and/or postsynaptic binding may be effective in stimulating sexual desire in animals and humans. The characterization of how those drugs work will help generate a rational approach to drug development in the treatment of HSDD. Pfaus JG. Pathways of sexual desire. J Sex Med 2009;6:1506-1533.