The Effects of Alprostadil on Hypothalamic and Amygdalar Function and the Central Expression of Oxytocin: A Potential Central Role of Alprostadil Cream

Our results suggest that the application of the alprostadil cream could act on the genital nerve terminals to facilitate the neurons of the PVN and BMA in the CNS, and increase the expression of oxytocin in the PVN to induce sex behaviors. Sun X, Xu L, Zhang J, Guo F, and Tang M. The effects of alprostadil on hypothalamic and amygdalar function and the central expression of oxytocin: A potential central role of alprostadil cream. J Sex Med 2009;6:81-90.