Establishment of a Transgenic Sickle-Cell Mouse Model to Study the Pathophysiology of Priapism

The morphometric changes of the penis and exaggerated in vivo erectile responses support the use of this transgenic sickle-cell disease animal model to study the pathophysiological mechanisms involved in sickle-cell disease-associated priapism. Bivalacqua TJ, Musicki B, Hsu LL, Gladwin MT, Burnett AL, and Champion HC. Establishment of a transgenic sickle-cell mouse model to study the pathophysiology of priapism. J Sex Med 2009;6:2494-2504.