Testosterone Increases Blood Flow and Expression of Androgen and Estrogen Receptors in the Rat Vagina

Our data suggest that testosterone regulates androgen and estrogen receptor protein expression in the vagina and enhances vaginal perfusion by an androgen-dependent mechanism. We conclude that testosterone plays an important role in modulating the physiology of the vagina and contributes to improvement of genital sexual arousal responses. Traish AM, Kim S Woong, Stankovic M, Goldstein I, and Kim NN. Testosterone increases blood flow and expression of androgen and estrogen receptors in the rat vagina.