Oxytocin Involvement in SSRI-Induced Delayed Ejaculation: A Review of Animal Studies

Preliminary data suggest that the severity of chronic SSRI treatment-induced delayed ejaculation and the differences between the various SSRIs in inducing ejaculation delay is related to gradual desensitization of 5-HT1A receptors on oxytocin neurons. de Jong TR, Veening JG, Olivier B, and Waldinger MD. Oxytocin involvement in SSRI-induced delayed ejaculation: A review of animal studies. J Sex Med 2007;4:14-28.