Understanding genetic analysis for breast cancer and its implications for plastic surgery

BRCA 1 and 2 mutations account for 5% to 10% of breast cancer cases. Women with high risk factors for BRCA 1 or 2 mutation should be referred to a medical oncologist and geneticist for counseling. A multidisciplinary approach is especially important in these cases, to provide counseling to patients regarding cancer risk, treatment options, and possible breast reconstruction methods. It is important for plastic surgeons to be involved in the treatment planning to discuss placement of biopsy and mastectomy incisions and also to adequately discuss realistic aesthetic expectations with the patient.