کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4278449 1611493 2015 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Infection susceptibility of crosslinked and non-crosslinked biological meshes in an experimental contaminated environment
ترجمه فارسی عنوان
حساسیت به عفونت شبکه های بیرونی متقابل و غیر متقابل در یک محیط آلوده تجربی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
چکیده انگلیسی

BackgroundThis experimental study investigates infectious complications and functional outcome of biological meshes in a contaminated environment.MethodsIn 90 rats peritonitis was induced, and after 24 hours, a biological mesh was implanted intraperitoneally including 2 non-crosslinked mesh groups (Strattice and Surgisis) and 2 crosslinked mesh groups (CollaMendFM and Permacol). Sacrifice was after 90 and 180 days.ResultsMore mesh infections occurred in crosslinked meshes compared with non-crosslinked meshes (70% vs 4%; P < .001). Mesh infection was the highest in crosslinked CollaMendFM (81.2%) and lowest in non-crosslinked Strattice groups (0%). Incorporation into the abdominal wall was poor in all meshes (0% to 39%). After 180 days no residue of non-crosslinked Surgisis mesh was found. After 180 days, shrinkage was .8% in crosslinked Permacol and 20% in Strattice groups. Strattice showed the least adhesion formation (median 5%).ConclusionsInfection rate of biological meshes in a contaminated field was the highest in crosslinked meshes. All biological meshes showed poor incorporation, which makes long-term abdominal wall repair questionable.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Surgery - Volume 210, Issue 1, July 2015, Pages 159–166
نویسندگان
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