کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4278731 1611501 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Results of a prospective thyroid ultrasound screening program in adenomatous polyposis patients
ترجمه فارسی عنوان
نتایج یک برنامه غربالگری سونوگرافی پیش آگهی تیروئید در بیماران مبتلا به پولیپ بینی آدنوماتوز
کلمات کلیدی
پولیپوز آدنوماتوز، سرطان تیروئید، غربالگری برای پیشگیری از سرطان
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
چکیده انگلیسی

BackgroundPatients with adenomatous polyposis may be at increased risk for developing thyroid cancer (TC). However, screening guidelines for TC in these patients are not well established.MethodsPatients with a diagnosis of familial adenomatous polyposis, attenuated familial adenomatous polyposis, and gene mutation-negative adenomatous polyposis enrolled in our Hereditary Colorectal Cancer Family Registry were eligible for a screening thyroid ultrasound (US). Findings were reviewed by the study endocrinologist and intervention and/or follow-up determined.ResultsFifty patients underwent screening thyroid US. Thirty-four (68%) patients had abnormal findings on US, including 27 (79%) with thyroid nodules. In 7 patients, US-detected thyroid nodules met established criteria for fine-needle aspiration. Of the 6 patients who underwent fine-needle aspiration, 2 (4%) were diagnosed with papillary TC. Both of these patients were female.ConclusionsA large proportion of adenomatous polyposis patients will have abnormal results on thyroid US, including suspicious-appearing thyroid nodules that when biopsied are malignant. Female patients have an apparently greater risk of developing TC. Polyposis patients, especially women, should be offered participation in a thyroid US screening program.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Surgery - Volume 208, Issue 5, November 2014, Pages 764–769
نویسندگان
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