کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4278829 | 1611513 | 2013 | 4 صفحه PDF | دانلود رایگان |
BackgroundFactors influencing the treatment of ductal carcinoma in situ with mastectomy and reconstruction are poorly understood.MethodsA retrospective cohort study of 196 patients presenting to one institution was performed.ResultsForty-seven patients (24.0%) were treated with mastectomy, while 149 (76.0%) underwent breast-conserving surgery. Of the mastectomy patients, 28 (59.6%) elected for reconstruction. On bivariate analysis, patients who opted for mastectomy were younger than those treated with breast-conserving surgery (median age, 51.8 vs 56.5 years; P = .017) and had higher grade tumors (50.0% vs 34.6% grade 3, P = .009). Among patients treated with mastectomy, those who opted for reconstruction were younger than those forgoing reconstruction (49.4 vs 56.9 years, P = .024). Race, ductal carcinoma in situ tumor size, and histologic subtype were not associated with the decision to pursue mastectomy or reconstruction (P > .05 for all).ConclusionsIn patients with ductal carcinoma in situ, the decision to pursue mastectomy and reconstruction appears to be driven by younger patient age and higher tumor grade.
Journal: The American Journal of Surgery - Volume 206, Issue 5, November 2013, Pages 682–685