کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4279219 1611533 2012 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The role of transcervical thymectomy in patients with hyperparathyroidism
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
The role of transcervical thymectomy in patients with hyperparathyroidism
چکیده انگلیسی

BackgroundThe most common location for supernumerary or ectopic parathyroid glands is the thymus.MethodsA review of patients who underwent parathyroidectomy for hyperparathyroidism from 1990 to 2010 was completed to determine indications for thymectomy, the yield of parathyroid tissue, and outcome of therapy.ResultsSeventy of 379 patients with hyperparathyroidism underwent parathyroidectomy and transcervical thymectomy. Intrathymic parathyroid tissue was present in 23 (33%) patients, including supernumerary glands in 8 patients (11%). Indications for thymectomy were renal hyperparathyroidism in 35 patients (50%) and primary hyperparathyroidism with a missing inferior gland in 20 patients (29%), an ectopic adenoma in 9 patients (13%), hyperplasia in 5 patients (7%), and carcinoma in 1 patient (1%). Cure rates were similar (96% and 98%; P = not significant) and only transient hypocalcemia was higher (51% vs 24%, P < .05) after parathyroidectomy with thymectomy versus parathyroidectomy alone.ConclusionsTranscervical thymectomy results in a high yield of parathyroid tissue and is essential for cure of selected patients with hyperparathyroidism.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Surgery - Volume 203, Issue 3, March 2012, Pages 292–296
نویسندگان
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