کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4279512 | 1611522 | 2013 | 9 صفحه PDF | دانلود رایگان |
BackgroundSurgical resection of bronchopulmonary carcinoid tumors can be curative and remains the primary treatment modality. There are limited data to delineate the optimal extent of resection for this disease.MethodsA retrospective review of the 3,270 patients diagnosed with typical and atypical carcinoid tumors between 2000 and 2007 in the Surveillance Epidemiology and End Results registry was performed.ResultsThe mean follow-up period was 46 months (range, 1–95 mo). Overall survival (OS) and disease-specific survival at 5 years was 80% and 90%, respectively. The mean OS was slightly better in the lobectomy group compared with those undergoing sublobar resection (86 vs 83 mo; P = .008). After adjusting for age, this finding was no longer present (P = .513). By using multivariate analysis, sublobar resection was noninferior to lobectomy with regard to disease-specific survival and OS (P < .05).ConclusionsCompared with lobectomy, sublobar resection is associated with noninferior survival in patients with typical carcinoid of the lung.
Journal: The American Journal of Surgery - Volume 205, Issue 2, February 2013, Pages 200–208