کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4279621 1611527 2012 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Targeted microbubbles in the experimental and clinical setting
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
Targeted microbubbles in the experimental and clinical setting
چکیده انگلیسی

BackgroundMicrobubbles have improved ultrasonography imaging techniques over the past 2 decades. Their safety, versatility, and easiness of use have rendered them equal or even superior in some instances to other imaging modalities such as computed tomography and magnetic resonance imaging. Herein, we conducted a literature review to present their types, general behavior in tissues, and current and potential use in clinical practice.MethodsA literature search was conducted for all preclinical and clinical studies involving microbubbles and ultrasonography.ResultsDifferent types of microbubbles are available. These generally improve the enhancement of tissues during ultrasonography imaging. They also can be attached to ligands for the target of several conditions such as inflammation, angiogenesis, thrombosis, apoptosis, and might have the potential of carrying toxic drugs to diseased sites, thereby limiting the systemic adverse effects.ConclusionsThe use of microbubbles is evolving rapidly and can have a significant impact on the management of various conditions. The potential for their use as targeting agents and gene and drug delivery vehicles looks promising.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Surgery - Volume 204, Issue 3, September 2012, Pages 355–366
نویسندگان
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