کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4279753 1611531 2012 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Thrombelastography-identified coagulopathy is associated with increased morbidity and mortality after traumatic brain injury
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
Thrombelastography-identified coagulopathy is associated with increased morbidity and mortality after traumatic brain injury
چکیده انگلیسی

BackgroundThe purpose of this study was to determine the relationship between coagulopathy and outcome after traumatic brain injury.MethodsPatients admitted with a traumatic brain injury were enrolled prospectively and admission blood samples were obtained for kaolin-activated thrombelastogram and standard coagulation assays. Demographic and clinical data were obtained for analysis.ResultsSixty-nine patients were included in the analysis. A total of 8.7% of subjects showed hypocoagulability based on a prolonged time to clot formation (R time, > 9 min). The mortality rate was significantly higher in subjects with a prolonged R time at admission (50.0% vs 11.7%). Patients with a prolonged R time also had significantly fewer intensive care unit–free days (8 vs 27 d), hospital-free days (5 vs 24 d), and increased incidence of neurosurgical intervention (83.3% vs 34.9%).ConclusionsHypocoagulability as shown by thrombelastography after traumatic brain injury is associated with worse outcomes and an increased incidence of neurosurgical intervention.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Surgery - Volume 203, Issue 5, May 2012, Pages 584–588
نویسندگان
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