کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4280239 | 1611555 | 2010 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Recurrence rates in breast cancer patients with false-negative intraoperative evaluation of sentinel lymph nodes Recurrence rates in breast cancer patients with false-negative intraoperative evaluation of sentinel lymph nodes](/preview/png/4280239.png)
BackgroundIntraoperative identification of sentinel lymph node (SLN) metastases in breast cancer patients results in synchronous axillary lymph node dissection. We examined the effect of false-negative SLN biopsy on breast cancer treatments and recurrence rate.MethodsPatient and tumor characteristics, intraoperative and final SLN biopsy results, and treatments of patients with and without recurrence were compared.ResultsRecurrence rates for patients with true-positive SLN biopsy (9%) were significantly higher than rates for false-negative SLN biopsy patients (2%). Recurrence rates were significantly higher for patients with primary tumors greater than 2 cm, positive lymph nodes greater than 2 mm, and tumors with negative hormone receptors, and varied with treatment extent.ConclusionsPatients with greater amounts of disease in the breast and axilla required more treatment and had a higher recurrence rate. False-negative SLN evaluation occurred more commonly in patients with less lymph node metastasis and was not associated with an increased recurrence rate.
Journal: The American Journal of Surgery - Volume 199, Issue 5, May 2010, Pages 625–628