کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4281012 1611571 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Management of the primary tumor in patients with metastatic pancreatic neuroendocrine tumor: a contemporary single-institution review
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
Management of the primary tumor in patients with metastatic pancreatic neuroendocrine tumor: a contemporary single-institution review
چکیده انگلیسی

BackgroundPancreatic nonfunctioning neuroendocrine tumors (PNFNETs) are an uncommon malignancy and often present with metastatic disease. There is a lack of information on the management of the primary tumor in patients who present with unresectable synchronous hepatic metastases.MethodsA retrospective review (2001–2008) of PNFNETs was conducted. Patients were divided into 3 groups: PNFNET without evidence of hepatic metastasis (group A), PNFNET with metastatic disease involving less than 50% of the liver (group B), and PNFNET with metastatic disease involving more than 50% of the liver (group C). Clinical data and outcomes were analyzed.ResultsThirty-five patients with PNFNET were identified (group A = 15, group B = 11, group C = 9). Resection of the pancreatic tumor was performed in 26 patients. With a mean follow-up period of 30 months, death from disease progression occurred in 1 patient in group A, none in group B, and in 7 in group C.ConclusionsIn selected patients, resection of the primary pancreatic tumor even in the setting of unresectable but limited hepatic metastases may be indicated.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Surgery - Volume 197, Issue 3, March 2009, Pages 376–381
نویسندگان
, , , , , , ,