کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4281432 | 1611588 | 2007 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Clinicopathologic features of papillary lesions on core needle biopsy of the breast predictive of malignancy Clinicopathologic features of papillary lesions on core needle biopsy of the breast predictive of malignancy](/preview/png/4281432.png)
BackgroundThe necessity for surgical excision of papillary lesions identified on percutaneous breast biopsy remains controversial. We reviewed data from patients with papillary lesions found on core needle biopsies to identify features associated with carcinoma.MethodsA retrospective chart review was performed on patients with papillary lesions diagnosed from image-guided breast biopsies over a 10-year period. Patients had surgical excision or were followed-up radiographically for a 2-year minimum.ResultsPapillary lesions were identified in 154 core needle biopsies. Ninety-five lesions were diagnosed as either benign or atypical. Eighty-nine of these patients had surgical excisions of their lesions. Malignancy was discovered in 22 (25%) of these lesions. Only atypical lesions on biopsy were malignant (P < .005). Forty-six percent of patients age 65 or older were found to have cancer at surgical excision (P < .01).ConclusionsPapillary lesions found on core needle biopsy frequently harbor malignancy (25%). Atypia and age 65 or older are significant risk factors for malignancy.
Journal: The American Journal of Surgery - Volume 194, Issue 4, October 2007, Pages 444–449