کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4281435 | 1611588 | 2007 | 4 صفحه PDF | دانلود رایگان |

BackgroundThe purpose of the study was to determine if ductal lavage could predict the occurrence of breast cancer as well as further stratify patients at high-risk for developing breast cancer.MethodsDuctal lavage was performed in 116 high-risk patients (Gail Risk score ≥1.7%, previous breast cancer, strong family history, previous suspicious biopsy specimen). If atypia or papillary cells were identified, a standard protocol of evaluation was initiated.ResultsTwo hundred twenty-three lavages were performed on 116 patients. Twenty-seven lavages in 25 patients yielded atypical or papillary-like cells. The 15 patients who underwent further evaluation for atypia had no evidence of cancerous or precancerous lesions. All patients were followed-up: 2 developed breast cancer, both of whom had had normal previous lavage. No patient with abnormal lavage developed cancer during follow-up.ConclusionsWe find ductal lavage to be of limited value in the screening of high-risk patients and have removed it from our treatment algorithm.
Journal: The American Journal of Surgery - Volume 194, Issue 4, October 2007, Pages 463–466