کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4281872 | 1611601 | 2006 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Accuracy of intraoperative imprint cytology of sentinel lymph nodes in breast cancer Accuracy of intraoperative imprint cytology of sentinel lymph nodes in breast cancer](/preview/png/4281872.png)
BackgroundIn breast cancer treatment, immediate completion of axillary lymph node dissection (ALND) can be performed if the intraoperative sentinel lymph node (SLN) examination is positive. This study evaluates the accuracy of intraoperative imprint cytology (IC) for detecting SLN metastases.MethodsPathology reports from 385 SLN biopsy examinations were reviewed retrospectively. The SLNs were serially sectioned perpendicular to the long axis and IC was performed intraoperatively. The SLNs then were formalin-fixed for permanent sections. Final pathology was compared with the intraoperative IC results.ResultsThe sensitivities for IC detection of N0(i+) (n = 36), N1mi (n = 24), and N1a-3a (n = 65) metastases were 0%, 4%, and 74%, respectively. The specificity was 100%.ConclusionsFinal pathology identified 89 (23%) patients with N1 or greater disease. IC allowed 49 (55%) of these patients to undergo synchronous completion of ALND. No unnecessary completion ALNDs were performed. The sensitivity of IC decreased with decreasing size of the metastasis.
Journal: The American Journal of Surgery - Volume 192, Issue 4, October 2006, Pages 516–519