کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4282012 1611608 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Positron-emission tomography as a prognostic tool for early-stage lung cancer
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
Positron-emission tomography as a prognostic tool for early-stage lung cancer
چکیده انگلیسی

BackgroundPositron-emission tomography (PET) shows tissue metabolic activity in the form of the standard uptake value (SUV). This study examines the prognostic value of the SUV for early-stage lung cancer.MethodsA retrospective review of 187 patients undergoing PET for potential lung cancer. Data collected included patient demographics, tumor pathology, and survival information. Data were correlated with PET results to determine if a prognostic relationship exists.ResultsThe sensitivity and specificity of PET for detecting malignant lesions were 98% and 24%. Malignant lesions had a higher SUV than benign lesions (5.9 ± 6.2 versus 2.2 ± 1.8, P < .0001). The average SUV of well-differentiated tumors was 2.6 ± 3.1 versus 5.9 ± 5.5 for other tumors (P = .010). There was a strong correlation between tumor stage and SUV (analysis of variance, P < .0001). There was no difference in tumor SUV for survivors versus nonsurvivors.ConclusionsThe SUV correlates with prognostic indicators, such as tumor stage and grade. The SUV alone was not an independent predictor of survival.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Surgery - Volume 191, Issue 3, March 2006, Pages 433–436
نویسندگان
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