کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4282527 1611745 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Should central lymph node dissection be considered for all papillary thyroid microcarcinoma?
ترجمه فارسی عنوان
آیا تشخیص گره لنفاوی مرکزی برای همه میکروارسینوما پاپیلر تیروئید در نظر گرفته می شود؟
کلمات کلیدی
گره لنفاوی مرکز سرطان تیروئید پاپیلری، میکروارسینومای پاپیلر تیروئید
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
چکیده انگلیسی

SummaryBackgroundCentral lymph node dissection (CLND) in patients with papillary thyroid microcarcinoma (PTMC) is still controversial. The aim of this study was to examine the risk factors and the incidence of central lymph node metastases (CLNMs) in patients with PTMC who underwent thyroidectomy and CLND.Patients and methodsBetween 2002 and 2013, 613 patients were enrolled who underwent thyroidectomy with routine CLND for PTMC at the Korea University Medical Center, Ansan Hospital and risk factors and the incidence of CLNM were analyzed. In addition, we also evaluated the complications after thyroidectomy with CLND.ResultsOut of 613 patients, 239 (39.0%) were found to have CLNM. Male sex (p = 0.012), tumor size ≥ 0.5 cm (p = 0.001), capsular invasion or extrathyroidal extension (p = 0.029), and multifocality (p = 0.004) were independent risk factors for CLNM. Among the 69 patients who had PTMC without these risk factors, CLNM was identified in 12 (17.4%). In this study group, two (0.3%) had permanent recurrent laryngeal nerve injury, two (0.3%) had persistent hypocalcemia, and two (0.3%) developed postoperative hemorrhage.ConclusionCLNM in PTMC is highly prevalent in male sex, tumor size ≥ 0.5 cm, extrathyroidal extension, and multifocality. Even in PTMC patients without these risk factors, the incidence of CLNM is rather higher than expected, and the complication rate of thyroidectomy with CLND is acceptable. Thus, CLND should be considered in all patients with PTMC.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Asian Journal of Surgery - Volume 39, Issue 4, October 2016, Pages 197–201
نویسندگان
, , , , , ,