کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4288043 1612039 2009 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect of Dai-kenchu-to on gastrointestinal motility and gastric emptying
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
Effect of Dai-kenchu-to on gastrointestinal motility and gastric emptying
چکیده انگلیسی

Background/aimsThe gastrointestinal symptoms accompanying dysfunction of the remnant stomach were seen after pylorus-preserving operation. Against such complications, Dai-kenchu-to (DKT) is used, but scientific evidences for efficacy are poor. The effect of DKT on gastrointestinal motility and gastric emptying after pylorus-preserving operation was investigated.MethodsUsing beagle dogs, the experimental models mimicking the state after pylorus-preserving pancreaticoduodenectomy were prepared. We sutured strain gauge transducers to the stomach, duodenum and jejunum and inserted indwelling tubes into the stomach. About 4 weeks after operation, DKT 0.1 g/kg was administered during the fasting or fed state. At the same time, the gastric emptying was evaluated by the acetoaminophene method.ResultsIn the fasting state, administration of DKT enhanced the gastrointestinal motility and accelerated gastric emptying. In the postprandial state, no apparent effect on motility was seen.ConclusionDKT enhances the gastrointestinal motility after pylorus-preserving pancreaticoduodenectomy in the fasting state. The effect of DKT may not be related to the continuity of the intramural nerve.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Surgery - Volume 7, Issue 3, 2009, Pages 218–222
نویسندگان
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