Asymptomatic adenocarcinoma arising from a gastric duplication cyst: A case report

• Adenocarcinoma arising from a gastric duplication cyst is extremely rare.
• This is the 2nd asymptomatic case in the English literature.
• During our close observation of 4 years, malignant transformation had occurred from a gastric duplication cyst.
• When morphological change appears, we strongly recommend surgical treatment without delay.

IntroductionDuplication of the alimentary tract is a relatively uncommon congenital anomaly and most cases occur in childhood. Malignancy arising from a gastric duplication cyst is extremely rare. We herein report a very rare case of malignant transformation of a gastric duplication cyst.Presentation of caseA 47-year-old asymptomatic Japanese woman was referred to our hospital with a large abdominal mass adhered to the stomach. Since there was a possibility of malignant transformation, complete resection of the cyst and segmental gastrectomy without regional lymphadenectomy were performed.DiscussionTo our knowledge, this is the 2nd report of asymptomatic adenocarcinoma arising from a gastric duplication cyst in the English-language literature. Unfortunately, the patient developed peritoneal metastasis and ascites seven months after the surgery and died.ConclusionFrom our long-term follow-up experience of this gastric duplication cyst, we recommend making accurate diagnosis as soon as possible with biopsy using endoscopic ultrasonography. When the disease is diagnosed as malignant, we recommend gastrectomy with lymphadenectomy. Even if the disease is diagnosed as benign, we recommend close observation with imaging modalities.