کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4288578 1612094 2016 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A rare case of lacrimal adenoid cystic carcinoma with large hepatic and multiple pulmonary metastases with successful surgical treatment
ترجمه فارسی عنوان
یک مورد نادر از کارسینوم آدنوئید کیست لاکریما با متاستازهای کبدی و چندگانه ریه با درمان جراحی موفق
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
چکیده انگلیسی


• Lacrimal gland adenoid cystic carcinoma present with late metastases.
• Surgery of the primary is the only proven mode of treatment with radiotherapy used in selected cases.
• Disseminated metastases can be managed successfully with staged procedures depending on the general condition of the patient.
• This is the first report describing such staged surgical treatment for widespread hepatic and pulmonary metastases with a good outcome.

IntroductionAdenoid cystic carcinoma (ACC) of the lacrimal gland is rare but with high recurrence rates and late metastases. They occasionally metastasise via haematogenous spread to lungs, brain and bone. Liver is a rare site of metastasis and is usually present with disseminated disease.Presentation of caseA 42 year old lady, a known case of adenoid cystic carcinoma of the lacrimal gland who had been operated 4 years ago for the same followed by chemotherapy and radiotherapy. She was detected with large hepatic and bilateral multiple pulmonary metastases. A right hepatectomy was done. After six months when her general condition improved we did a staged pulmonary metastatectomy. Histology confirmed the diagnosis. She is presently doing well with no recurrence since 18 months.DiscussionUsually asymptomatic, the commonest symptom is pain. It is a locally invasive disease with a poor prognosis if detected late. Surgery is the only proven therapy. Isolated hepatic metastases being managed surgically has been reported. However, extensive, staged, surgical resection of hepatic and pulmonary metastases has not been reported.ConclusionLacrimal ACC is an aggressive tumour with known late metastases with the liver being affected seldomly. Our case highlights that even disseminated metastases to the liver and the lungs from lacrimal ACC can be managed surgically with a good outcome. To our knowledge, no such report with distant metastases to the liver and the lung along with their successful surgical management has been reported.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Surgery Case Reports - Volume 20, 2016, Pages 151–154
نویسندگان
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