Congenital agenesis of pubis and bilateral cryptorchidism: A case report

• Agenesis of the pubis is a very rare clinical deformity which can be a sign of urogenital abnormalities. To report a rare condition would help clinicians to diagnose co-morbidities which may affect children remaining life.
• This is a rare pattern of associated anomalies confined to a localized region of the body. Somatic mutations may responsible for developmental abnormalities of mesoderm from which the pubic bones and urogenital structures develop.
• An isolated X-ray finding of ramus pubis agenesis may associate with cryptorchidism or several other urogenital malformations.

INTRODUCTIONAgenesis of the pubic bone, as evidenced in the world literature, is a very rare clinical and congenital abnormality. Several disorders may occur with hypoplasia of the pubis.PRESENTATION OF CASEHere, we report a rare longer follow-up case of the congenital unilateral agenesis of the superior ramus of pubic bone with bilateral undescended testes, osteoporosis, cranial malformations, acetabular dysplasia, unilateral shortening of the lower extremity and an abnormal gait pattern.DISCUSSIONSomatic mutations may responsible for developmental abnormalities of the mesoderm from which the pubic bones and urogenital structures develop.CONCLUSIONAn isolated x-ray finding of ramus pubis agenesis may associate with cryptorchidism or several other urogenital malformations.