کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4299009 | 1288378 | 2007 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Intraoperative Margin Re-Resection for Colorectal Liver Metastases Intraoperative Margin Re-Resection for Colorectal Liver Metastases](/preview/png/4299009.png)
ObjectiveEvaluate recurrence and survival in patients who underwent intraoperative margin re-resection for colorectal cancer liver (CRC) metastases.DesignRetrospective analysis.SettingUniversity Hospital, Cincinnati, Ohio. Academic medical center.ParticipantsCohort of 118 patients who underwent resection of CRC liver metastases between 1992 and 2004. All patients were divided into 3 groups: resection margin (MOR) less than 1 cm (n = 64), MOR greater than 1 cm (n = 33), and re-resection margin (re-MOR) greater than 1 cm (n = 21).ResultsPatients with a margin greater than 1 cm, when compared with re-MOR greater than 1 had decreased incidence of liver and distant recurrence (p < 0.05) as well as improved disease-free survival (39.2 vs 22.9 months, p = 0.023). Differences in overall survival (58.6 vs 44.2 months, p = 0.14) were not significant.ConclusionIntraoperative re-resection is associated with an increased risk of local and distant recurrence, which may be a reflection of both inadequate surgery and underlying tumor biology.
Journal: Journal of Surgical Education - Volume 64, Issue 3, May–June 2007, Pages 150–157