کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4301091 1288432 2013 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Tissue-engineering repair of extrahepatic bile ducts
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
Tissue-engineering repair of extrahepatic bile ducts
چکیده انگلیسی

BackgroundIn recent years, with the widespread use of laparoscopic cholecystectomy and liver transplantation, complications involving the biliary system are increasing. All techniques available have a high risk of recurrence or high-morbidity problems. We developed a three-dimensional collagen duct modified with agarose hydrogel, to substitute the affected extrahepatic bile duct.Materials and methodsWe used it in 40 guinea pigs and studied the histology and physiology at 4 wk, 3, and 6 mo after transplantation. Blood test, histologic techniques, and cholangiography were performed in all of them.ResultsAll experimental animals survived up to their sacrifices. Our graft showed highly potential applications to treat hepatobiliary diseases that require surgery.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Surgical Research - Volume 179, Issue 1, January 2013, Pages 18–21
نویسندگان
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