Glucose-Induced Intestinal Vasodilation Via Adenosine A1 Receptors Requires Nitric Oxide but Not K+ATP Channels

These data suggest that glucose-induced vasodilation of premucosal jejunal arterioles is mediated through adenosine A1 receptors, and NO at least partially mediates the adenosine A1 receptor-induced vasodilation. In addition, K+ATP channels are not involved in premucosal arteriolar vasodilation during intestinal glucose exposure.