کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4303151 1288472 2010 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Radiofrequency Ablation of Liver Tumors: A Novel Needle Perfusion Technique Enhances Efficiency
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
Radiofrequency Ablation of Liver Tumors: A Novel Needle Perfusion Technique Enhances Efficiency
چکیده انگلیسی

ObjectiveWe hypothesize that perfusion of an expandable radiofrequency ablation (RFA) needle with saline solution might help prevent charring and increase efficiency.Summary Background DataRFA has become an important adjunct to modern liver surgery. However, ablation is time-consuming and hazardous due to charring around the radiofrequency electrodes.MethodsFrom June 2000 to November 2004, 159 liver tumors with a median diameter of 2.0cm were treated with RFA, 54 tumors of them according to the manufacturer's standard protocol and 105 tumors according to the novel perfusion protocol. No randomization was applied. All patients were followed up with contrast enhanced computed tomography (CT) at regular intervals. Local recurrence was defined as radiologic and/or histologic evidence of viable tumor within or at the ablated liver area.ResultsBoth study groups were comparable with regard to tumor characteristics, procedure related complications, and median times of follow-up (27 mo in the standard group versus 23 mo in the perfusion group). The median RFA time was significantly reduced from 18.9 min in the standard group to 8.0 min in the perfusion group. The rates of incomplete ablations were comparable in both groups (3.7% versus 2.8%). The rate of local recurrences at the RFA site was 6.9% overall, 11.1% in the standard group, and 4.8% in the perfusion group. No tumor seeding along the puncture channel was observed.ConclusionsThe perfusion of an expandable RFA needle with saline solution significantly accelerates the ablation procedure of liver tumors without increase of complications and without compromising the oncosurgical result.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Surgical Research - Volume 159, Issue 1, March 2010, Pages 532–537
نویسندگان
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