کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4313270 | 1289992 | 2011 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Age-related differences in the anticipation of future rewards Age-related differences in the anticipation of future rewards](/preview/png/4313270.png)
The present study examined the anticipation of future reward in 7-mo- and 26-mo-old Fischer 344/Brown Norway rats. Young and old rats were divided randomly and assigned into one of two conditions. In the Contrast Condition, subjects were given a water solution containing 2% sucrose for 3 min followed immediately by a water solution containing 32% sucrose for 3 min. In the No-Contrast Condition, subjects were given a water solution containing 2% sucrose for 3 min followed immediately by a water solution containing 2% sucrose for 3 min. Across 10 days of testing in the Contrast Condition, young rats showed significantly less intake of the less preferred 2% sucrose solution, whereas old rats showed increased intake of the 2% sucrose solution. Young rats showed a significant increase in intake of the preferred 32% sucrose solution compared to aged rats across the 10-day testing period with the exception of days 8–10 where intake did not differ between groups. In the No-Contrast Condition, there were no significant differences between young and old rats, with both groups consuming significantly more of the first 2% solution than the second 2% solution. Therefore, these data suggest that age-related changes may impair the ability to anticipate future rewards.
► The study investigated age-related changes in the ability to anticipate future rewards in rats.
► Young rats decreased intake of a less preferred stimulus in anticipation of a preferred stimulus.
► Old rats increased intake of a less preferred stimulus and did not anticipate a preferred stimulus.
► Old rats show significant deficits compared to young rats in the anticipation of future rewards.
Journal: Behavioural Brain Research - Volume 223, Issue 2, 1 October 2011, Pages 371–375