Reprint of: Effects of BDNF polymorphisms on brain function and behavior in health and disease

► BDNF has been implicated in cognitive function as well as the pathogenesis of various psychiatric disorders. ► Studies suggested BDNF Val66Met polymorphism related to various mental diseases, but not all reports support these findings. ► These conflicting findings may result from confounding factors such as age, gender, and phenotype assessment.