Isoform-specific expression and ratio changes accompany oxidant-induced peripherin aggregation in a neuroblastoma cell line

► Peripherin isoform-specific expression changes in response to oxidative stress. ► Changes in Per-58 and Per-45 alter normal expression stoichiometry. ► Peripherin-specific aggregation accompanies oxidative damage. ► Despite widespread cellular oxidation, peripherin aggregates were not carbonylated.