Differential effects of zinc influx via AMPA/kainate receptor activation on subsequent induction of hippocampal CA1 LTP components

►Zinc influx into hippocampal cells facilitates via AMPA/kainate receptor activation. ►The zinc influx attenuates subsequent induction of NMDA receptor-dependent CA1 LTP. ►NMDA receptor-independent CA1 LTP is less susceptibility to the zinc influx. ►Zinc influx differentially acts on the induction of CA1 LTP components.