کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4329496 | 1614218 | 2008 | 11 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: The mechanism of magnetic field-induced increase of excitability in hippocampal neurons The mechanism of magnetic field-induced increase of excitability in hippocampal neurons](/preview/png/4329496.png)
The influence of a pulsed magnetic field (PMF) on hippocampal evoked potentials has been investigated in vitro. The exposure to PMF (0.16 Hz, 15 mT) applied for 30 min amplified the population spike and the slope of EPSP recorded from stratum pyramidale and stratum radiatum respectively. This amplification was additive to previously induced LTP and occurred in an NMDA-independent way. The increase in the activity of electrical synapses accompanied PMF-induced amplification of evoked potentials. Since PMF exposure modified paired-pulse facilitation and paired-pulse inhibition, it was concluded that it modifies excitatory and inhibitory processes in the hippocampus. Control experiments revealed that observed effects were exclusively related to PMF exposure. The results support and extend our previous research indicating a significant influence of magnetic fields on hippocampal physiology.
Journal: Brain Research - Volume 1221, 24 July 2008, Pages 30–40