کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4329703 1614222 2008 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The role of the anterior intraparietal sulcus in crossmodal processing of object features in humans: An rTMS study
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
The role of the anterior intraparietal sulcus in crossmodal processing of object features in humans: An rTMS study
چکیده انگلیسی

Investigations in macaques and humans have shown that the anterior intraparietal sulcus (IPS) has an important function in the integration of information from tactile and visual object manipulation. The goal of this study was to investigate the special functional role of the anterior IPS in visuo–tactile matching in humans. We used the “virtual-lesion” technique of repetitive transcranial magnetic stimulation (rTMS) to test the functional relevance of anterior IPS for visuo–tactile crossmodal matching. Two crossmodal (visual encoding and tactile recognition and vice versa) and two unimodal delayed matching-to-sample tests with geometrical patterns were performed by 12 healthy subjects. We determined error rates before and after focal low-frequency rTMS applied over the left anterior IPS, right anterior IPS and vertex. During the manipulation of objects with the right hand, rTMS over the left anterior IPS induced a significant deterioration for visual encoding and tactile recognition, but not for tactile encoding and visual recognition. For the visual and tactile unimodal conditions, no significant alterations in task performance were found. rTMS application over right IPS when manipulating objects with the left hand did not affect crossmodal task performance. In conclusion, we have demonstrated an essential functional role of the left anterior IPS for visuo–tactile matching when manipulating objects with the right hand. However, we found no clear evidence for left IPS involvement in tactile encoding and visual recognition. The differential effect of rTMS on tactile and visual encoding and recognition are not consistently explained by previous concepts of visuo–tactile integration.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain Research - Volume 1217, 27 June 2008, Pages 110–118
نویسندگان
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