کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4330075 | 1614241 | 2008 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Collateral projections from the subfornical organ to the median preoptic nucleus and paraventricular hypothalamic nucleus in the rat
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کلمات کلیدی
SFONTSVLMFSRAngiotensin II - آنژیوتانسین دوAng II - دومretrograde tracing - ردیابی عقب ماندهFast Blue - سریع آبیSubfornical organ - عضو زیربنیکیSON - فرزند پسرPVN - مالیات بر ارزش افزودهventrolateral medulla - مدول ونتیلاتورSupraoptic nucleus - هسته Supraopticnucleus tractus solitarius - هسته دستگاه انفرادیparaventricular hypothalamic nucleus - هسته هیپوتالاموس پروژستیکPOME - پوم
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
It is morphologically demonstrated that the subfornical organ (SFO) projects to the paraventricular hypothalamic nucleus (PVN) and also projects to the nucleus preopticus medianus (POMe), a relay nucleus of indirect projections from the SFO to PVN. However, it remains unknown, whether or not SFO neurons project collaterally to the POMe and PVN. To confirm this, a double retrograde labeling method was performed on rats using two fluorescent tracers. One tracer (red-colored FluoSpheres: FSR) was injected into the POMe and the other (Fast Blue: FB) was injected into the unilateral PVN at the same time. As a result, many retrogradely labeled neurons were found in the entire SFO. Of these, some neurons showed both FSR and FB fluorescence. Double-labeled neurons were found in about 8.7% of FSR-labeled neurons and 15.5% of FB-labeled neurons. The existence of double-labeled neurons indicates that single neurons in the SFO project simultaneously to the POMe and PVN via collateral axon branches. The data suggest that there are complicated neuronal pathways originating from the SFO in regulating cardiovascular and body fluid homeostasis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain Research - Volume 1198, 10 March 2008, Pages 68-72
Journal: Brain Research - Volume 1198, 10 March 2008, Pages 68-72
نویسندگان
Ping-Guo Duan, Hitoshi Kawano, Sadahiko Masuko,