کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4335620 1295170 2010 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A novel delayed non-match to sample object recognition task that allows simultaneous in vivo microdialysis
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
A novel delayed non-match to sample object recognition task that allows simultaneous in vivo microdialysis
چکیده انگلیسی
We present a modification of the widely used delayed non-match to sample (DNMS) paradigm for assessment of object recognition memory that can be combined with simultaneous in vivo microdialysis. The present study provides evidence that hippocampal ACh release increases from baseline during active exploration of the test environment and an empty test board, but a specific further increase is seen during the recognition memory task performance. This novel experimental model offers a good tool to study the impact of selective lesions or pharmacological manipulation simultaneously on neurotransmitter levels and memory task performance.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Neuroscience Methods - Volume 189, Issue 2, 15 June 2010, Pages 210-215
نویسندگان
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