کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4338277 | 1614854 | 2012 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Focal electrical intracerebral stimulation of a face-sensitive area causes transient prosopagnosia Focal electrical intracerebral stimulation of a face-sensitive area causes transient prosopagnosia](/preview/png/4338277.png)
Face perception is subtended by a large set of areas in the human ventral occipito-temporal cortex. However, the role of these areas and their importance for face recognition remain largely unclear. Here we report a case of transient selective impairment in face recognition (prosopagnosia) induced by focal electrical intracerebral stimulation of the right inferior occipital gyrus. This area presents with typical face-sensitivity as evidenced by functional neuroimaging right occipital face area (OFA). A face-sensitive intracerebral N170 was also recorded in this area, supporting its contribution as a source of the well-known N170 component typically recorded on the scalp. Altogether, these observations indicate that face recognition can be selectively impaired by local disruption of a single face-sensitive area of the network subtending this function, the right OFA.
► Transient prosopagnosia from human brain intracerebral stimulation is reported.
► The recognition impairment is specific to faces.
► The area stimulated is functionally defined as the right ‘occipital face area’.
► A face-sensitive N170 potential is recorded directly in this area.
Journal: Neuroscience - Volume 222, 11 October 2012, Pages 281–288