کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4338398 1614860 2012 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Interactions between two propagating waves in rat visual cortex
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Interactions between two propagating waves in rat visual cortex
چکیده انگلیسی

Sensory-evoked propagating waves are frequently observed in sensory cortex. However, it is largely unknown how an evoked propagating wave affects the activity evoked by subsequent sensory inputs, or how two propagating waves interact when evoked by simultaneous sensory inputs. Using voltage-sensitive dye imaging, we investigated the interactions between two evoked waves in rat visual cortex, and the spatiotemporal patterns of depolarization in the neuronal population due to wave-to-wave interactions. We have found that visually-evoked propagating waves have a refractory period of about 300 ms, within which the response to a subsequent visual stimulus is suppressed. Simultaneous presentation of two visual stimuli at different locations can evoke two waves propagating toward each other, and these two waves fuse. Fusion significantly shortens the latency and half-width of the response, leading to changes in the spatial profile of evoked population activity. The visually-evoked propagating wave may also be suppressed by a preceding spontaneous wave. The refractory period following a propagating wave and the fusion between two waves may contribute to visual sensory processing by modifying the spatiotemporal profile of population neuronal activity evoked by sensory events.


► Visually-evoked cortical waves were examined with voltage-sensitive dye imaging.
► Evoked waves suppressed subsequent evoked waves during a window of 80–300 ms.
► Simultaneously evoked waves propagated toward each other and fused.
► Fusion significantly changed the spatiotemporal profile of propagation.
► Occurrence of spontaneous waves suppressed visually-evoked waves.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 216, 2 August 2012, Pages 57–69
نویسندگان
, , , , , ,