Dorsal root ganglia isolated from Nf1+/− mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels

▶In wildtype mice, Nav1.9 was the most abundant subtype with Nav1.7 and Nav1.8 the next most abundant. ▶Nav1.1, Nav1.3, Nav1.7, and Nav1.8 were significantly elevated in DRG isolated from Nf1+/− mice. ▶Nav1.2, Nav1.5, Nav1.6, and Nav1.9 were not significantly altered. ▶Expression of the auxiliary β subunits (β1-β4) was not different.