Expression, phosphorylation, and glycosylation of CNS proteins in aversive operant conditioning associated memory in Lymnaea stagnalis

▶The phosphorylation and the glycosylation levels of proteins increase during memory formation. ▶Identified phosphoproteins are associated with G-protein signaling, energy metabolism, etc. ▶Increased actin phosphorylation is associated with memory formation. ▶Up-regulated proteins are associated with protein and nucleic acid synthesis, cytoskeleton, etc. ▶Down-regulated proteins are enzymes of aspartic acid metabolism.