کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4339129 1614897 2011 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Subtype-specific reduction of voltage-gated calcium current in medium-sized dorsal root ganglion neurons after painful peripheral nerve injury
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Subtype-specific reduction of voltage-gated calcium current in medium-sized dorsal root ganglion neurons after painful peripheral nerve injury
چکیده انگلیسی
▶We examine neuronal Ca2+ current loss that follows painful peripheral nerve injury. ▶Ca2+ current in DRG neurons decreases for both L- and N-channel subtypes. ▶This effect is evident during both square and AP waveform depolarizations. ▶The activation curve shifts right for N-type current after injury. ▶Injury does not affect N-type channel number or unitary current.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 179, 14 April 2011, Pages 244-255
نویسندگان
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